The IRES absolute position (the range includes START and STOP codons or their equivalents): 1-494
How IRES boundaries were determined: experimentally_determined
The sequence of IRES region aligned to its secondary structure (if available):
This IRES represents full-length 5'-UTR (1-494 bp) of AEV mRNA.
The AEV IRES element displays resistance to an inhibitor of eIF4A and functions well in the presence of
Mutational analyses of AEV IRES shows similarities of AEV with HCV and PTV-1 IRES in domains IIIE and IIIf.
Deletion of 100 nt from the 5' end of the 5' UTR (mutant AEVm3) had some effect on IRES activity in cells,
reducing the activity to 50% of the activity of the wild type (wt).